Gram-positive cocci in clusters, catalase positive, tube coagulase negative, novobiocin susceptible. Which organism is most likely?

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Multiple Choice

Gram-positive cocci in clusters, catalase positive, tube coagulase negative, novobiocin susceptible. Which organism is most likely?

Distinguishing Staphylococcus species uses catalase status, coagulase activity, and novobiocin susceptibility. The Gram-positive cocci in clusters that are catalase positive place you in the Staphylococcus genus. A negative tube coagulase test rules out Staphylococcus aureus, which is typically coagulase positive. Among the coagulase-negative staphylococci, novobiocin susceptibility differentiates S. saprophyticus (usually resistant) from the others (usually susceptible). Because this organism is coagulase negative and novobiocin susceptible, the best fit is a coagulase-negative staphylococcus, such as Staphylococcus epidermidis.

Distinguishing Staphylococcus species uses catalase status, coagulase activity, and novobiocin susceptibility. The Gram-positive cocci in clusters that are catalase positive place you in the Staphylococcus genus. A negative tube coagulase test rules out Staphylococcus aureus, which is typically coagulase positive. Among the coagulase-negative staphylococci, novobiocin susceptibility differentiates S. saprophyticus (usually resistant) from the others (usually susceptible). Because this organism is coagulase negative and novobiocin susceptible, the best fit is a coagulase-negative staphylococcus, such as Staphylococcus epidermidis.

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