Which antibiotic class should be avoided when treating Enterococcus infections?

Prepare for the CAMLPR Microbiology Test. Utilize flashcards and engaging multiple-choice questions, each equipped with descriptions and explanations. Ready yourself for an excellent performance!

Multiple Choice

Which antibiotic class should be avoided when treating Enterococcus infections?

Explanation:
Enterococcus species have intrinsic resistance to cephalosporins because their penicillin‑binding proteins bind these drugs poorly, so cephalosporins fail to inhibit cell wall synthesis effectively. This means they’re unlikely to treat Enterococcus infections and can lead to persistent infection. Other classes like vancomycin, linezolid, and daptomycin can be active against Enterococcus depending on the strain’s susceptibility, so they’re preferred choices when appropriate.

Enterococcus species have intrinsic resistance to cephalosporins because their penicillin‑binding proteins bind these drugs poorly, so cephalosporins fail to inhibit cell wall synthesis effectively. This means they’re unlikely to treat Enterococcus infections and can lead to persistent infection. Other classes like vancomycin, linezolid, and daptomycin can be active against Enterococcus depending on the strain’s susceptibility, so they’re preferred choices when appropriate.

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