Which antibiotic is listed as a treatment option for Bacteroides fragilis?

Prepare for the CAMLPR Microbiology Test. Utilize flashcards and engaging multiple-choice questions, each equipped with descriptions and explanations. Ready yourself for an excellent performance!

Bacteroides fragilis is an anaerobic Gram-negative rod that often requires antibiotics effective against anaerobes and beta-lactamase producers. Piperacillin-tazobactam pairs an extended-spectrum penicillin with a beta-lactamase inhibitor, tazobactam, which blocks the enzymes B. fragilis may produce. This combination broadens the antibiotic’s activity to include B. fragilis and many other Gram-negative bacteria, making it a robust option for polymicrobial infections where anaerobic coverage is needed. While other agents like metronidazole or carbapenems can also treat B. fragilis, the piperacillin-tazobactam option is a well-established choice for comprehensive anaerobic and Gram-negative coverage in a single regimen. Cefepime tends to have limited anaerobic activity, and is less reliable for B. fragilis alone.