Which antibiotic is used to treat Neisseria gonorrhoeae?

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Multiple Choice

Which antibiotic is used to treat Neisseria gonorrhoeae?

Ceftriaxone is the best choice because it remains reliably effective against Neisseria gonorrhoeae, despite widespread resistance to older antibiotics. As a third-generation cephalosporin, it kills the bacteria by inhibiting cell wall synthesis and penetrates mucosal sites where gonorrhea typically resides, making it a strong, dependable option. Penicillin and ciprofloxacin have largely failed due to resistant strains, so they are no longer dependable treatments. Azithromycin is sometimes added to cover potential co-infection with Chlamydia trachomatis, but it is not sufficient on its own as the primary therapy because of rising resistance. Therefore, ceftriaxone is the most appropriate primary treatment, often used with azithromycin for concurrent infections.

Ceftriaxone is the best choice because it remains reliably effective against Neisseria gonorrhoeae, despite widespread resistance to older antibiotics. As a third-generation cephalosporin, it kills the bacteria by inhibiting cell wall synthesis and penetrates mucosal sites where gonorrhea typically resides, making it a strong, dependable option. Penicillin and ciprofloxacin have largely failed due to resistant strains, so they are no longer dependable treatments. Azithromycin is sometimes added to cover potential co-infection with Chlamydia trachomatis, but it is not sufficient on its own as the primary therapy because of rising resistance. Therefore, ceftriaxone is the most appropriate primary treatment, often used with azithromycin for concurrent infections.

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