Prepare for the CAMLPR Microbiology Test. Utilize flashcards and engaging multiple-choice questions, each equipped with descriptions and explanations. Ready yourself for an excellent performance!

Multiple Choice

Which organism is associated with cystic fibrosis and demonstrates oxidase-positive, motile bacteria with glucose oxidation showing yellow in the O tube and green in the F tube?

The main idea here is recognizing a nonfermenting, oxidase-positive Gram-negative rod that shows oxidative metabolism of glucose. In the oxidative (O) vs fermentation (F) test, an organism that oxidizes glucose but does not ferment it will turn the O tube yellow due to acid production, while the F tube stays green because fermentation doesn’t occur. This oxidation-dominant pattern helps identify certain nonfermenters commonly seen in the CF lung. Burkholderia cepacia is a classic example: it’s oxidase-positive, motile, nonfermenting, and, in the lab, often shows glucose oxidation with yellow in the O tube and green in the F tube. Its association with cystic fibrosis is a key clinical clue, since B. cepacia can cause serious, rapidly progressive infection in CF patients and requires strict infection-control measures. While other oxidase-positive nonfermenters can share similar oxidation patterns, the combination of this metabolic profile plus the CF link points to Burkholderia cepacia in this context.

The main idea here is recognizing a nonfermenting, oxidase-positive Gram-negative rod that shows oxidative metabolism of glucose. In the oxidative (O) vs fermentation (F) test, an organism that oxidizes glucose but does not ferment it will turn the O tube yellow due to acid production, while the F tube stays green because fermentation doesn’t occur. This oxidation-dominant pattern helps identify certain nonfermenters commonly seen in the CF lung.

Burkholderia cepacia is a classic example: it’s oxidase-positive, motile, nonfermenting, and, in the lab, often shows glucose oxidation with yellow in the O tube and green in the F tube. Its association with cystic fibrosis is a key clinical clue, since B. cepacia can cause serious, rapidly progressive infection in CF patients and requires strict infection-control measures. While other oxidase-positive nonfermenters can share similar oxidation patterns, the combination of this metabolic profile plus the CF link points to Burkholderia cepacia in this context.